Sample MCAT Question - Peptide Bonds
Which of the following is true about peptide bonds?
I. No free rotation
II. Require enzymes to break these bonds
III. Breaking these bonds is exergonic
a) I and II only
b) I and III only
c) II and III only
d) I, II, and III
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Intro to Peptide Bonds
Amino acids are the monomer building blocks of peptides and proteins. In other posts, we discussed the structure and configuration of amino acids, their classification (as polar, nonpolar, etc.), and their protonation states and isoelectric point. In this post, however, we’ll discuss how amino acids link together via peptide bonds and how these bonds can be broken via hydrolysis. We’ll also discuss the special resonance character of peptide bonds, which gives them extra strength.
Alexi Caffelle
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